The aim of this prospective study was to evaluate the correlation between tumor blood flow (TBF) measurement using pseudo-continuous arterial spin labeling (pCASL) and parameters of DCE-MRI in patients with head and neck squamous cell carcinoma (HNSCC). We scanned 26 patients with HNSCC using 3T MRI with both pCASL and DCE-MRI. There were significant correlation between TBF of pCASL and wash-in, signal enhancement ratio, and Vp of DCE-MRI, with a correlation coefficient of 0.649, 0.642, and 0.507, respectively (P<0.01). The pCASL can be a useful tool for noninvasive assessments of the TBF in patients with HNSCC.
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