Abstract #5400

Quantitative MR Neurography with Robust Fat Suppression

Masami Yoneyama¹, Akio Hiwatashi², Xinzeng Wang³, Osamu Togao², Ivan E. Dimitrov^4,5, Ananth J. Madhuranthakam^3,4, Iain Ball⁶, and Marc Van Cauteren⁷

¹Philips Japan, Tokyo, Japan, ²Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ³Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, ⁴Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, ⁵Philips Healthcare, Gainesville, FL, United States, ⁶Philips Healthcare Australia, North Ryde, Australia, ⁷Philips Healthcare Asia Pacific, Tokyo, Japan

MR neurography plays a major role in the diagnostic work-up of peripheral nerve pathologies and a quantitative evaluation based on T₂ values can be clinically useful in estimating treatment effects and determining prognosis. Recently, we proposed a new sequence (SHINKEI-Quant) to add a quantitative information to MR neurography. To solve some issues caused by the current fat suppression techniques (SPAIR and STIR), we propose to combine SHINKEI-Quant with a new two-point dual-echo 3D DIXON-TSE (DE-mDIXON) technique. SHINKEI-Quant with DE-mDIXON simultaneously provides both MR neurography with high SNR, uniform fat suppression, and T₂ maps with T₂ values similar to conventional method. This sequence may be helpful to quantitatively assess nerve pathology.

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