Abstract #5288

Utility of Combination Image of T2-weighted and FLAIR using Synthetic MRI for Improved Lesion Contrast in Multiple Sclerosis

Yasuhiro Fujiwara¹, Yumi Inoue², Masayuki Kanamoto³, Shota Ishida³, Toshiki Adachi³, and Hirohiko Kimura⁴

¹Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, ²Schoo of Health Sciences, Kumamoto University, Kumamoto, Japan, ³Radiological Center, University of Fukui Hospital, Fukui, Japan, ⁴Department of Radiology, University of Fukui, Fukui, Japan

To improve multiple sclerosis plaque, we attempted to produce Synthetic FLAIR3 (SyFLAIR3) combined from FLAIR and T2WI using Synthetic MRI. The purpose of this study was to determine optimal contrast weighting for SyFLAIR3 and to evaluate whether the SyFLAIR3 can improve the T2 contrast on WM. To effectively suppress CSF signal for SyFLAIR3, it was necessary to optimize the combination of TE for T2WI and FLAIR. The optimized SyFLAIR3 using Synthetic MRI makes it possible to improve contrast in MS lesion.

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