Abstract #5199

Ultrashort Echo Time-MRI of proximal femoral cortical bone in patients with osteoporosis

Dimitri MARTEL¹, Mary BRUNO¹, H.Michael BELMONT², Amit SAXENA², Gabrielle TURYAN¹, Stephen HONIG³, Ravinder R. REGATTE¹, and Gregory CHANG¹

¹Radiology, NYU Langone Health, New York, NY, United States, ²Department of Rheumatology, NYU Langone Health, New York, NY, United States, ³Osteoporosis Center, Hospital for Joint Diseases, NYU Langone Health, New York, NY, United States

Ultra-short echo time MRI (uTE-MRI) allows exploration of the role of cortical bone properties in osteoporosis. OP can be primary or can also be induced by drugs such as glucocorticoids (glucocorticoid-induced osteoporosis, GIO).No previous studies have assessed cortical porosity in GIO patients compared to OP patients.Our aim was to perform uTE-MRI of cortical bone of the proximal femur (a common site of fracture) in GIO patients and compare the results to those of OP patients using a bi-exponential fitting procedure of uTE images.

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