Abstract #5177

CPPD-diseased, Normal and Degenerated Menisci: Biomechanical and quantitative MRI-derived Properties

Tim Finkenstaedt^1,2, Reni Biswas³, Nirusha Abeydeera³, Palanan Siriwanarangsun^3,4, Robert Healey⁵, Sheronda Statum³, Won C. Bae³, and Christine B. Chung^3,6

¹Department of Radiology, University of California, School of Medicine, San Diego, CA, USA, San Diego, CA, United States, ²Department of Radiology, University Hospital Zurich, Zurich, Switzerland, ³Department of Radiology, University of California, San Diego, School of Medicine, USA, San Diego, CA, United States, ⁴Department of Radiology, Siriraj Hospital, Bangkok, Thailand, ⁵Department of Orthopaedic Surgery, University of California, San Diego, School of Medicine, USA, San Diego, CA, United States, ⁶Department of Radiology, VA San Diego Healthcare System, San Diego, CA, United States

Calcium pyrophosphate crystal deposition (CPPD) disease of the knee is a frequent condition in the elderly population that might cause chondrocalcinosis of the fibrocartilaginous menisci. Controversy exists whether chondrocalcinosis of the menisci is a cause or consequence of osteoarthritis. Thus, it would be desirable to determine whether CPPD-afflicted menisci exhibit altered biomechanical properties and if they correlate with quantitative MR values. Purpose of this study is to investigate if CPP deposits alter the biomechanical properties as well as the UTE values of menisci compared to grossly normal and degenerated human menisci.

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