No study already evaluated how arterial blood flow is transferred from extracranial to intracranial level and how venous outflow is transferred from intracranial sinuses to jugular veins. Healthy young and elderly volunteers were enrolled and underwent phase contrast magnetic resonance imaging to investigate intracranial and extracranial arterial and venous flows. In both groups, we found a significant decrease of arterial and venous flows pulsatilities inside the cranium. However, the intracranial and extracranial cerebral blood flow pulsatilities increased significantly with age.
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