Abstract #4911

Simultaneous multislice spiral cine DENSE MRI

Changyu Sun¹, Yang Yang², Xiaoying Cai ¹, Sophia Cui¹, Daniel Auger¹, Michael Salerno^1,2,3, and Frederick H. Epstein^1,3

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Medicine, University of Virginia, Charlottesville, VA, United States, ³Radiology, University of Virginia, Charlottesville, VA, United States

Spiral cine DENSE is an established method for imaging myocardial strain, however a relatively long acquisition time is a limitation. We developed a simultaneous multislice (SMS) method to accelerate spiral cine DENSE imaging. For SMS excitation we employed CAIPIRINHA phase modulation of the multiple slices. For the SMS reconstruction, we implemented a modified iterative conjugate gradient sensitivity encoding (CG-SENSE) method. Simulations and experiments in phantoms show that a 10-15% error occurs when imaging two slices simultaneously. Two-slice volunteer SMS images showed close agreement with separately-acquired single-slice images. SMS with CG-SENSE may be an effective means to accelerate spiral cine DENSE.

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