Hepatic MRE is a promising non-invasive tool for diagnosing liver fibrosis. To facilitate clinical translation, we developed a method to eliminate the need for mechanical actuators for wave generation. Propagation of the transient cardiac shear waves within the liver caused by cardiac-valve closure can be imaged at a very high temporal resolution (0.3ms) using a 2D motion-sensitised pencil beam, with total data acquisition time fitting into four consecutive breath holds. These images were used to estimate liver stiffness, with a high temporal resolution allowing for reliable fitting to the space-time images and thus robust speed estimates.
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