This study aimed to investigate the clinical diagnostic utility of ZOOMit-DWI-based IVIM imaging technology[1,2] for periampullary lesions. Forty-one patients, comprising cancer of the pancreatic head (n = 6), chronic pancreatitis (n = 9), ampullary adenocarcinoma (n = 9), and distal bile duct carcinoma (n = 17) and 28 healthy volunteers were enrolled. Our results showed that the perfusion fraction (f) of the IVIM-derived parameter has the potential to distinguish between cancer of the pancreatic head, other lesions, and normal tissue in the periampullary regions by using the zoomed DW imaging, which has the capacity to overcome some of the limitations of conventional MRI of the pancreas.
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