fMRI is the gold standard of human functional brain imaging, although functional near-infrared spectroscopy (fNIRS) is easier to administer and lower in cost. Therefore studies have tried to compare the two techniques. However results have been variable, partly due to only rough spatial correspondence between fMRI and fNIRS, and systemic physiological noise influences. In the current study we use a previously described multimodal fNIRS/fMRI probe with optodes directly integrated into the coil structure. We characterize the spatial and temporal overlap between task-evoked fMRI and fNIRS signal, as well as their systemic physiological influences with high spatial and temporal correspondence.
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