Accurate T1 estimation is critical for quantitative prostate DCE MRI. B1+ inhomogeneity can introduce significant error into the T1 quantification, especially for variable flip angle method. Reference region variable flip angle (RR-VFA) method is a promising B1+ and T1 estimation technique, which requires no separate scans for B1+ mapping and can reduce slice profile and position mismatch between B1+ and T1 maps. In this study, we investigated both intra-scanner repeatability and inter-scanner reproducibility regarding B1+ corrected T1 on two 3.0 T scanners to compare RR-VFA to a commercially available B1+ estimation technique. RR-VFA showed comparable
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