Abstract #4486

Restriction Spectrum Imaging-A Novel Diffusion-Based Technique for Detection and Characterization of Prostate Cancer

Ely R Felker¹, Leonard Marks², Fuad Elkhoury², David Lu¹, Daniel Margolis³, Sepideh Shakeri¹, Pooria Khoshnoodi⁴, Lorna Herbert², Nathan White⁵, David Karow⁶, and Steven Raman¹

¹Radiology, UCLA, Los Angeles, CA, United States, ²Urology, UCLA, Los Angeles, CA, United States, ³Radiology, Cornell, New York, NY, United States, ⁴Pathology, University of Minnesota, Minneapolis, MN, United States, ⁵UCSD, San Diego, CA, United States, ⁶Human Longevity Institute, San Diego, CA, United States

We evaluated the utility of restriction spectrum imaging (RSI), a novel diffusion-based technique to detect and to characterize prostate cancer among men enrolled in a national cancer institute-funded prospective clinical trial of magnetic resonance ultrasound fusion biopsy. RSI was statistically significantly associated with clinically significant prostate cancer.

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