Abstract #4249

Time efficient whole-brain coverage in Magnetic Resonance Fingerprinting using echo-planar imaging, slice-interleaving and simultaneous multi-slice imaging

Benedikt Rieger^1,2, Mehmet Akçakaya^2,3, Lothar Schad¹, and Sebastian Weingärtner^1,2,3

¹Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, ²Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ³Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States

Magnetic resonance fingerprinting (MRF) is a promising method for simultaneous multi-parameter quantification. However, spatial coverage is limited in the original method due to the rapid image readout and the balanced sequence design. The aim of this study is to enable time-efficient volumetric coverage in Cartesian MRF-EPI for whole-brain quantification in clinically acceptable scan times. A slice-interleaved acquisition is shown to offer quantification precision comparable to single-slice measurements in a fraction of the measurement time. By combining this with simultaneous multi-slice imaging, whole-brain coverage with 40 slices was achieved in one minute, resulting in high quality T₁ and T₂* maps.

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