To optimize spoiling efficiency, we evaluate several design choices for RF- and gradient-spoiling in MPRAGE-type sequences. Optimization is performed using two efficient algorithms, one for the ideal-spoiling condition, and one for a 3D extended phase graph model that realistically captures spoiling effects. We used novel implementations of both algorithms, with publicly available source, that attempt to maximize computational efficiency. Our results suggest possible avenues for improving spoiling in MPRAGE-type sequences.
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