Recently, 7T-MR system has been approved for clinical use in Europe and USA; however, its clinical configuration is limited to single-channel transmit so B1+ shimming is not feasible. This study investigated reproducibility of single-voxel MRS using short-TE STEAM and semi-LASER using a single-transmit & 32-receiver head coil at 7T. Fifteen healthy young volunteers were scanned twice at the posterior cingulate. SNR was higher in semi-LASER, but coefficients of variation were comparable ranging mainly from 5-10% and better in short-TE STEAM in low-concentration J-coupled peaks. Even with clinical setups, 7T shows high reliability and will contribute to MRS investigation.
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