Sodium ion (Na+) is a very important factor in the physiology of the human eye. However sodium (23Na) MRI is limited by its low sensitivity. Compressed sensing provides means to overcome this challenge. This work demonstrates the feasibility of high spatial resolution (1mm isotropic) 23Na in vivo MRI of the eye using a dedicated six-channel transceiver array in conjunction with a 3D dictionary learning compressed sensing algorithm. This approach showed distinct noise reduction along with substantial reduction in total acquisition time if benchmarked against conventional reconstruction employing standard gridding.
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