The diffusion property of tumor tissues largely depends on cell density, which may also be predictive features of malignancy in some types of tumors. Intravoxel incoherent motion (IVIM) imaging is an extension of diffusion weighted imaging (DWI) that can be used to investigate both diffusion and perfusion changes in tissues. Comparing the IVIM parameters between carcinoma (HCC), hepatic hemangioma and hepatic metastasis, we found that IVIM can facilitates understanding of tumor tissue characteristics of perfusion and diffusion, and it may provide more useful information to distinguish hemangiomas from other two malignant tumors.
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