4D-MRI sequence for radiotherapy (RT) application is validated in this study on a motion phantom and on healthy volunteers. 4D-MR imaging of a moving spherical target with different signal waveforms gave similar results as for classical 4D-CT used in RT planning. During free breathing 4D-MRI acquisitions, the internal surrogates, defined as the mean intensity inside a region of interest are relevant to detect the different respiratory phases for consistent retrospective automatic image sorting. Feasibility of integration into treatment planning system was also demonstrated, allowing picturing the dynamic behavior of the moving organ for treatment planning.
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