Abstract #3790

Multi-modal MRI investigation of brain plasticity during prolonged Braille learning in sighted subjects – voxel-based morphometry and quantitative T1 mapping approach

Bartosz Kossowski¹, Jacek Matuszewski¹, Łukasz Bola^1,2, Anna Banaszkiewicz¹, Małgorzata Paplińska³, Michał Szczepanik¹, Marcin Szwed², Katarzyna Jednoróg⁴, and Artur Marchewka¹

¹Laboratory of Brain Imaging, Nencki Institute of Experimental Biology, Warsaw, Poland, ²Department of Psychology, Jagiellonian University, Kraków, Poland, ³Academy of Special Education, Warsaw, Poland, ⁴Laboratory of Psychophisiology, Nencki Institute of Experimental Biology, Warsaw, Poland

In order to study structural brain reorganization, multi-modal MRI combining voxel-based morphometry and quantitative T1 mapping was used in longitudinal design on sighted subjects who underwent tactile Braille reading course. Results show that methods are complimentary to each other. Combined approach like that gives insight into different aspects of tissue property changes introducing new opportunities for studying brain plasticity.

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