We examined 40 patients with neurological and hepatic form of Wilson disease by susceptibility mapping at 3T and T1 and T2 relaxometry at 1.5T and 3T. We were able to distinguish patients with neurological form from hepatic form and healthy controls based on quantitative relaxometry and susceptibility mapping. Higher susceptibility observed in the globus pallidus, putamen, and caudate nucleus in patients with neurological form corresponds to higher iron content while higher susceptibility in the thalamus corresponds rather to demyelination.
This abstract and the presentation materials are available to members only; a login is required.