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Abstract #3685

Applications of ZTE-derived Attenuation Correction Maps to Neuropediatric Cases: A Preliminary Analysis

Brice Fernandez1, Gaspar Delso2, Gisèle Depas3, Maya Khalifé4, Irène Buvat5, Claude Comtat5, and Catherine Chiron3

1Applications & Worflow, GE Healthcare, Orsay, France, 2Applications & Workflow, GE Healthcare, Cambridge, United Kingdom, 3INSERM U1129, Université Paris Descartes, CEA-SHFJ, Paris, France, 4Centre de NeuroImagerie de Recherche (CENIR), Institut du Cerveau et de la Moelle épinière (ICM), Paris, France, 5Imagerie Moléculaire In Vivo, IMIV, CEA, INSERM, CNRS, Université Paris-Sud, Université Paris Saclay, CEA-SHFJ, Orsay, France

PET/MR is a promising imaging modality for pediatric applications due to its lower radiation dose compared to PET/CT. However, commonly implemented MR-derived Attenuation Correction (MRAC) methods have not been fully evaluated for pediatrics brain applications. Consequently, we aimed at comparing different MRAC methods (Atlas, ZTE and High-resolution ZTE) on pediatric patients. Since the current gold standard AC data (i.e. CT) is missing, the different MRAC methods are ranked in comparison with the results found in the literature to determine if current knowledge regarding MRAC methods applied on adults might be extended to the considered pediatric population.

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