Abstract #3320

Global left ventricular myocardial deformation measures by CMR tissue tracking in isolated diastolic dysfunction (DD) spontaneous T2DM rhesus monkeys: comparison with tagging

Tong Zhu¹, Li Gong², Yushu Chen¹, Yu Zhang¹, Wen Zeng², Jie Zheng³, and Fabao Gao^1,2

¹Department of Radiology, Sichuan University, Chengdu, China, ²Sichuan Primed Biotech Group Co., LTD, Chengdu, China, ³Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States

In this study, the myocardial deformation characteristics of early diabetic cardiomyopathy were evaluated by using CMR strain imaging in a spontaneous non-human primate T2DM disease model. We found the early cardiac dysfunction characteristics of diabetic cardiomyopathy, and verified the effectiveness of CMR-tissue tracking in its early diagnosis.

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