Abstract #3140

Automated MR-based volumetry of basal ganglia and thalamus at the chronic phase of cortical stroke

Cindy Baudat¹, Bénédicte Maréchal^1,2,3, Ricardo Corredor-Jerez^1,2,3, Patric Hagmann¹, Philippe Maeder¹, and Vincent Dunet¹

¹Department of Diagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland, ²Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, ³Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

We investigated the potential of automated T1-MPRAGE-based brain segmentation to assess individual basal ganglia and thalamus atrophy in nineteen patients with cortical stroke at the chronic phase. The basal ganglia and thalamus volumes z-scores were compared to the initial stroke ipsilateraly and contralateraly, and the relationship with the stroke volume was assessed. Except caudate nucleus, basal ganglia and thalamus, atrophy ipsilateraly to the stroke was observed and negatively correlated with the stroke volume in the territory of the middle cerebral artery. This suggests a potential role for automated MRI volumetry to assess brain plasticity after stroke at the individual level.

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