Severe sepsis is one of the leading cause of death in the intensive care units (ICU) or in short time after discharge from ICU. Developing a rat model of early sepsis involving caecal ligation and puncture, we undertaken this cardiac MRI study to quantitatively assess myocardial function and the protective effect of dietary EPA. Our results showed that, in the exception of the rate of contraction, cardiac functions are less impacted in the early hyperdynamic phase of sepsis with no/or milder modulation of dietary EPA.
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