Abstract #2990

Retrospective Multi-Phase Non-Contrast-Enhanced Magnetic Resonance Angiography (ROMANCE MRA) for Robust Angiogram Separation in the Presence of Cardiac Arrhythmia

Hahnsung Kim^1,2, Suhyung Park^1,3, Eung Yeop Kim⁴, Chul-Ho Sohn⁵, and Jaeseok Park¹

¹Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea, ²Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ³Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States, ⁴Department of Radiology, Gachon University Gil Medical Center, Incheon, Republic of Korea, ⁵Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea

In the proposed ROMANCE MRA, data were continuously acquired over all cardiac phases using retrospective, multi-phase flow-sensitive single-slab 3D fast spin echo (FSE) with variable refocusing flip angles, while an external pulse oximeter was in sync with pulse repetitions in FSE to record real-time information on cardiac cycles. Data were then sorted into k-bin space using the real-time cardiac information. Angiograms were reconstructed directly from k-bin space by solving a constrained optimization problem with both subtraction-induced sparsity and low rank priors. Peripheral MRA was performed in a normal volunteer and a volunteer with cardiac arrhythmia using conventional fresh blood imaging (FBI) and the proposed ROMANCE MRA for comparison.

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