Strong T2* weighting has allowed high sensitivity of HiSS breast MRI to cancer, but in whole-breast imaging, contrast is compromised due to necessarily shorter echo trains. k-space under-sampling techniques such as compressed sensing (CS) yield time savings that can be traded for longer echo trains and stronger T2* weighting, potentially increasing breast HiSS MRI performance in screening and diagnostic applications. Our CS simulation resulted in minimal reduction in spatial resolution for acceleration factor R = 2, showing CS to be a promising acceleration strategy for HiSS MRI, allowing longer echo trains and stronger T2* weighting.
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