Abstract #2775

In vivo feasibility of T1-corrected Dual-TR Chemical Shift Encoded Fat Quantification Method

Xiaoke Wang¹, Diego Hernando^2,3, and Scott Reeder^1,2,3,4,5

¹Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

In chemical shift encoded (CSE) fat quantification techniques, a low flip angle is most commonly used to avoid T1 bias at the expense of SNR. Alternatively, dual flip angle (DFA) acquisitions can be used for T1-corrected fat quantification, however DFA doubles the scan time. A dual TR (DTR) method is proposed where a small percentage increase of scan time allows the independent estimation of T1 of water and fat, and T1-correced fat quantification. This work demonstrates the feasibility of DTR in phantoms and liver imaging.

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