Abstract #2604

Demonstration of linear correlation between R2* and liver iron concentration across multiple MR acquisition parameters at 1.5T and 3T.

Richard Hayden Jones¹, Jason Bentley², Valentina Taviani³, Diego Hernando⁴, Scott Reeder⁵, and Shreyas Vasanawala¹

¹Radiology, Lucile Packard Children's Hospital, Palo Alto, CA, United States, ²Stanford University of Medicine Quantitative Sciences Unit, Stanford University, Palo Alto, CA, United States, ³GE Healthcare, Sunnyvale, CA, United States, ⁴Radiology, Medical Physics, University of Wisconsin, Madison, WI, United States, ⁵Radiology, Biomedical Engineering, Medical Physics, University of Wisconsin, Madison, WI, United States

We demonstrate a robust linear relationship between the concentration of liver iron and R2* measurements taken in any liver segment, with various planes of acquisition, slice thickness, flip angle, and echo spacing at 1.5T or 3T. As compared with Ferriscan, R2* imaging is faster, lower-cost, and requires no post-processing, and has better geographic availability compared to the gold standard of superconducting quantum interference devices.

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