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Abstract #2494

Application of T1rho and T1 mapping MRI in Tracking Renal Ischemia Reperfusion Injury Process in Rats

Yangguang Yuan1,2, Jingjing Huang1, Yingjie Mei3, Siying Wang4, and Wen Liang1

1Medical Image Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China, 2Radiology Department, Shenzhen Luohu People’s Hospital, Shenzhen, China, 3Philips Healthcare, Guangzhou, China, 4Philips Healthcare, Shanghai, China

Previous studies using T1rho and T1 mapping in the liver and heart demonstrated that T1rho value and T1 relaxation time can be used to assess acute injury and long-term tissue fibrosis1. However, to the best of our knowledge, these techniques have not been explored to evaluate acute kidney ischemia damage. In our study, we found that T1rho value and T1 relaxation time showed high specificity and sensitivity in a rat renal ischemia reperfusion injury (IRI) model.

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Abstract