Abstract #2464

Temporal and spatial evaluation of pulmonary blood flow using multiple delay PCASL at 1.5 Tesla

Ferdinand Seith¹, Rolf Pohmann², Martin Schwartz^3,4, Thomas Küstner^3,4, Klaus Scheffler^2,5, Konstantin Nikolaou¹, Fritz Schick³, and Petros Martirosian³

¹Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany, ²Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ³Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, ⁴Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, ⁵Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Pseudo-continuous-arterial-spin-labeling (PCASL) has been successfully applied in abdominal organs to image organ perfusion. The aim of this work was to evaluate the pulmonary blood flow in dependence on the cardiac cycle using PCASL at 1.5T. Labeling of pulmonary blood flow was achieved by ECG triggering and an labeling plane perpendicular to the pulmonary trunk (tagging duration 300ms). In five volunteers, eight measurements were acquired with fast True-FISP imaging (in-plane-resolution, 2.5×2.5mm², coronal view) with post-labeling delays between 100 and 1500ms. The PCASL-True-FISP technique was able to precisely assess blood flow of pulmonary arteries, as well as perfusion of the lung parenchyma.

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