Abstract #2443

A Study of Lung Function Variability in Chronic Obstructive Pulmonary Disease Using Hybrid Hyperpolarized 3He Imaging

Hooman Hamedani¹, Ryan Baron¹, Sarmad Siddiqui¹, Yi Xin¹, Mary Spencer¹, Faraz Amzajerdian¹, Stephen Kadlecek¹, Kai Ruppert¹, Mehrdad Pourfathi¹, Luis Loza¹, Ian Duncan¹, Tahmina Achekzai¹, Maurizio Cereda², and Rahim R. Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States

To better understand variable lung function in COPD, we imaged a subset of COPDGene subjects at baseline, one week post-baseline and one month post-baseline using a multifaceted hyperpolarized (HP) ³He scheme to measure apparent diffusion coefficient (ADC), fractional ventilation (FV), alveolar oxygen tension (P_AO₂) and oxygen uptake (R) variability.

This abstract and the presentation materials are available to members only; a login is required.

Join Here