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Abstract #2381

Field strength dependent somatosensory-evoked mouse fMRI: 9.4 T vs. 15.2 T

Won Beom Jung1,2, Hyun-Ji Shim1,3, Sangwoo Kim1, and Seong-Gi Kim1,2,3

1Cener for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS), Suwon, Republic of Korea, 2Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea, 3Department of Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea

BOLD fMRI is highly sensitive to magnetic field strength. However, there is a notion that 7–9.4T is an optimal field strength for fMRI and higher fields do not increase BOLD signal changes. Here, we compared the BOLD response in the mouse somatosensory cortex at both magnetic fields of 9.4T and 15.2T to determine the BOLD dependence on magnetic field strength and found that the BOLD fMRI response is indeed increased as the field strength increases.

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