Abstract #2372

Brain activity during the training period of the Hybrid Assistive Limb (HAL) for a subacute stroke: an fMRI case report

Kousaku Saotome¹, Akira Matsushita², Aiki Marushima³, Hiroaki Kawamoto⁴, Hideo Tsurushima¹, Masashi Yamazaki⁵, Akira Matsumura³, and Yoshiyuki Sankai¹

¹Center for Cybernics Research, University of Tsukuba, Tsukuba, Japan, ²Department of Neurosurgery, Ibaraki Prefectural University of Health Sciences Hospital, Ami, Japan, ³Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ⁴Faculty of Engineering, Information and Systems, University of Tsukuba, Tsukuba, Japan, ⁵Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

The effectiveness of hybrid assistive limb (HAL) training, which is the new rehabilitation robotic approach, for recovery of brain function after stroke remains to be clarified. This is the first report to show the brain activation alteration during the training period for HAL for subacute stroke by using motor task-based functional magnetic resonance imaging (fMRI) 4 times. Our major finding was that fMRI results demonstrated rearrangement of the cortical activation pattern in a form that induces cerebral lateralization in M1 toward the contralateral hemisphere.

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