While a consensus exists on the benefits of background suppression for brain ASL to reduce physiological noise, conflicting results have been presented for renal applications. Furthermore, bulk motion management remains a challenge for clinical applications. In the current work, we investigate the effects and interactions between background suppression and retrospective motion-correction when used for single-slice free-breathing renal ASL. We emphasize the influence of BS and motion-correction on thermal and physiological noise levels and show that BS is critical for renal ASL using pCASL while retrospective motion-compensation helps in increasing image sharpness.
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