Abstract #2170

Simultaneous Acquisition of ASL, BOLD effect, Phase and QSM for Functional Multi-Parametric Brain Studies

Sagar Buch¹, Hacene Serrai¹, and Ravi S. Menon^1,2

¹Center for Functional and Metabolic Mapping, Robarts Research Institute, Western University, London, ON, Canada, ²Medical Biophysics, Western University, London, ON, Canada

A 2D-GRE-EPI based sequence combined with the PICORE magnetization preparation technique was used to acquire functional Arterial Spin Labeling (ASL) perfusion data at high field (7T). BOLD and Cerebral Blood Flow (CBF) changes along with phase and susceptibility maps (QSM) are obtained and assessed from this scan. Using a pre-determined general linear model (GLM), a strong correlation between the change in these parameters in the activated region (visual cortex) has been found showing that this multi-parametric acquisition may help in resolving the multi-factorial BOLD signal for functional brain studies.

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