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Abstract #2155

Differentiation of grade II/III and Grade IV glioma by combining ‘T1 contrast enhanced brain perfusion imaging’ and susceptibility weighted quantitative imaging

Jitender Saini1, Pradeep Kumar Gupta2, Prativa Sahoo3, Anup Singh4, Rana Patir5, Sunita Ahlawat6, Manish Beniwal7, K. Thennarasu8, Vani Santosh9, and Rakesh Kumar Gupta2

1Department of Neuroimaging & Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India, 2Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India, 3Beckman Research Institute, Mathematical Oncology, Duarte, CA, United States, 4Center for Biomedical Engineering, Indian Institute of Technology Delhi, Delhi, India, 5Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, India, 6SRL Diagnostics, Fortis Memorial Research Institute, Gurgaon, India, 7Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India, 8Department of Biostatistics, National Institute of Mental Health and Neurosciences, Bangalore, India, 9Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Heard Island And Mcdonald Islands

The purpose of this study is to evaluate the usefulness of T1-perfusion MRI and SWI in discriminating among grade II, III and IV gliomas. We found that combining T1-perfusion and SWI improves the diagnostic accuracy for discrimination of grade III from grade IV gliomas and T1-perfusion MRI derived rCBV alone appears to be an excellent measure for discriminating grade II from grade III glioma.

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Abstract