Abstract #2138

Gadolinium concentration map based on synthetic MRI and its application to brain metastases

Misaki Nakazawa¹, Akifumi Hagiwara^1,2, Christina Andica¹, Masaaki Hori¹, Moeko Horita^1,3, Koji Kamagata¹, Haruyoshi Houshito¹, and Shigeki Aoki¹

¹Department of Radiology, Juntendo University School of Medicine School of Medicine School of Medicine, Tokyo, Japan, ²Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ³Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan

Signal intensity measured on T1-weighted image is not proportional to the gadolinium concentration in vivo after administration of contrast agent. Thus, some calculations are required to estimate gadolinium concentration using quantitative values before and after gadolinium administration. We created gadolinium concentration maps that directly show the amount of contrast agent using quantitative maps calculated using synthetic MRI. The gadolinium concentration map we created using phantoms showed high accuracy and precision. The gadolinium concentration map could reliably measure the concentration of gadolinium in metastatic brain tumors.

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