Abstract #1955

Comparison between two different post-processing techniques in the presurgical evaluation of Focal Cortical Displasya in a paediatric population.

Elena Bassanelli¹, Maria Camilla Rossi Espagnet², Nicola Pietrafusa³, Luca De Palma³, Nicola Specchio³, Daniela Longo², and Antonio Napolitano¹

¹Medical Physics Department, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy, ²Imaging Department, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy, ³Department of Neurosciences, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy

The purpose of this study is to compare two different techniques for cortical dysplasia detection: Opti-MAP and the SUPR-FLAIR. The Opti-MAP is a children-optimized version of the Morphological analysis program (MAP), which is able to detect the “blurred-junction”, peculiar characteristics of focal cortical dysplasia in children, thanks to a voxel-based morphological analysis in which neuroanatomical differences are detected by comparison with a normal template. The SUPR-FLAIR analysis, instead, is a technique able to highlight hyperintensities in FLAIR images. These methods have been applied on paediatric subjects affected by pharmaco-resistant epilepsy.

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