Myelination is one of the essential indicators of brain maturation, and various abnormalities in myelin content have been found for different psychiatric disorders. However, reliable imaging techniques for human in vivo myelin measurement are still under intensive research, thus the degree and significance of myelin deficits for specific pathology remain indeterminate. The current study compared myelin mapping proposed as part of the Human Connectome Protocol using the ratio of T1 and T2 weighted image intensity to quantitative magnetization transfer mapping (qMT). The relationship between myelin content estimated by these two methodologies in various brain regions is discussed.
This abstract and the presentation materials are available to members only; a login is required.