Oxytocin (OT) and arginine vasopressin (AVP) exert sexually dimorphic effects on cognition and emotion processing in healthy individuals, and abnormalities in these neuroendocrine systems are observed in schizophrenia with a sex-dependent manner. Here we examined sex-dependent hormone associations with resting brain activity by applying resting-fMRI and their clinical associations in schizophrenia patients relative to healthy controls. We found that hormones differentially associate with brain networks, the sex-dependent alternation of hormone and brain activity are important for cognition and emotion processing in men and women with schizophrenia.
This abstract and the presentation materials are available to members only; a login is required.