The pathogenesis of DON and diplopia is totally different. This study use the MRI-DTI on DON and diplopia patients with good therapeutic efficacy, the multiple DTI parameters of optic nerve were calculated and assessed. The final results furtherly confirmed this difference. And the statistical difference of DTI parameter changes in DON patients validate the DTI can exactly, objectively and reliably detect the microstructure and functional repair of optic nerve after iv MP therapy.
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