Abstract #1589

Reproducibility of Diffusion Tensor Imaging Data between Morning and Evening Scans

Domitille Dempuré^1,2, Jia Fan^2,3, André J.W. van der Kouwe⁴, Ernesta M. Meintjes^2,3,5, and A. A. Alhamud^2,3,5

¹Higher Institute of Bioscience of Paris (ISBS), Paris, France, ²MRC/UCT Medical Imaging Research Unit, Division of Biomedical Engineering, University of Cape Town, Cape Town, South Africa, ³Department of Human Biology, University of Cape Town, Cape Town, South Africa, ⁴Massachusetts General Hospital, Boston, MA, United States, ⁵Cape Universities Body Imaging Centre (CUBIC-UCT), Cape Town, South Africa

Diffusion Tensor Imaging (DTI) is widely used to study brain white matter integrity. However, instability of the MRI scanner including heating of the iron plates in the shim trays or physiological changes during the day may influence DTI indices. The aim of this work was to evaluate DTI parameters through scans performed at two different times of the day, early morning and late afternoon, and repeated over six days. The results showed that DTI data acquired at different times of day differed, as mean diffusivity was higher in the morning than the evening.

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