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Abstract #1541

Tumor Metabolism, Diffusion, and Perfusion in Head and Neck Cancer: Pretreatment Multimodality Imaging with DCE-MRI, IVIM DW-MRI, 18F-FMISO PET/CT, and 18F-FDG PET/CT

David Aramburu Nunez1, Milan Grkovski1, Nancy Lee2, Vaios Hatzoglou3, Heiko Schoder3, Ramesh Paudyal1, Nadeem Riaz2, Joseph O Deasy1, John Humm1, and Amita Shukla-Dave4

1Medical Physics, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, 2Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, 3Radiology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States, 4Medical Physics and Radiology, Memorial Sloan-Kettering Cancer Center, New York City, NY, United States

The aim of this study is to understand the correlation of pretreatment quantitative imaging metrics obtained from multimodality imaging (MMI) techniques, such as DCE-MRI, IVIM DW-MRI, 18F-FMISO PET/CT, and 18F-FDG PET/CT giving us a comprehensive characterization of the tumor in head and neck cancer (HNC) patients. The results show complementary, rather than competitive, information about tumor metabolism, diffusion, and per­fusion.

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