Abstract #1519

Assessment of Approximated Analytical B1+ Correction Method for prostate DCE-MRI with Multiple Noise Levels and in 3.0 T Systems

Xinran Zhong^1,2, Thomas Martin^1,2, Steve Raman¹, Holden H Wu^1,2, Krishna Nayak³, and Kyunghyun Sung^1,2

¹Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, ²Physics and Biology in Medicine IDP, University of California, Los Angeles, Los Angeles, CA, United States, ³Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA, United States

B₁⁺ correction is essential for quantitative prostate DCE-MRI. A simplified approximated analytical B₁⁺ correction method was proposed previously, and we assess this method on a digital reference object (DRO) with various SNR levels and on 110 in-vivo cases from two 3.0 T systems. We find that the approximated analytical B₁⁺ correction method achieves comparable performance to conventional correction method with substantially reduced computation. The approximated analytical correction method is simple and practical for application in the clinic.

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