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Abstract #1500

Mechanism of Stable Cavitation Induced Signal Intensity Changes in Fast Spin Echo Images

Cheng-Tao Ho1, Chen-Hua Wu1, Po-Hung Hsu2, Hao-Li Liu3, Chih-Kuang Yeh1, Ching-Hsiang Fan1, Wen-Shiang Chen4,5, and Hsu-Hsia Peng1

1Department Of Biomedical Engineering And Environmental Sciences, National Tsing Hua University, Hsinchu City, Taiwan, 2Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taoyuan city, Taiwan, 3Department Of Electrical Engineering, Chang-gung University, Taoyuan city, Taiwan, 4Department Of Physical Medicine And Rehabilitation, National Taiwan University Hospital, Taipei city, Taiwan, 5Division Of Medical Engineering Research, National Health Research Institutes, Miaoli city, Taiwan

The purpose of this study was to comprehend the mechanism of stable cavitation (SC)-induced signal intensity (SI) changes by fast spin-echo images in a phantom with flowing MBs. We postulated that the different patterns of SI changes might be related to transmitting FUS pulses at different timing of k-line acquisitions. The SC-induced microstreaming and shear force could generate hypo- and hyper-SI changes, respectively. In conclusion, the illustration of the mechanism could be helpful for designing experiments in monitoring SC-induced SI changes.

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