Collagenous matrix, bound and pore water pools are main responsible components for viscoelastic properties of the cortical bone. Quantitative ultrashort echo time MR imaging (UTE-MRI) has been shown to be able to assess bound and pore water components as indexes for bone microstructure. UTE magnetization transfer (UTE-MT) modelling can evaluate the macromolecular (MM) components of the bone (collagen). Pixel mapping of MR properties of collagen and water components in cortical bone helps to localize pathologic or traumatic bone defects. This study focused on deriving the pixel maps of MR properties of these key bone components on seven bovine bone specimens.
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