Abstract #1317

The Effect of B0 and B1+ Inhomogeneities on Spinal Cord MRS

Nicholas Maurice Simard¹, Aimee J Nelson², and Michael D. Noseworthy^1,3

¹School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, ²Department of Kinesiology, McMaster University, Hamilton, ON, Canada, ³Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada

Spinal cord ¹H MR Spectroscopy (¹H-MRS) is a promising method for musculoskeletal research. However, due to the spine’s anatomical location there is a significant degradation of signal quality due to magnetic field inhomogeneities, rendering most MRS approaches inaccurate. Although there has been measurement of ΔB₀ in spinal cord MRS, there are no comprehensive assessments of temporal changes in B₀ and B₁⁺ relating physiological disturbances with MRS accuracy. Thus our goal was to continually measure temporal changes in B₀and B₁⁺ during the length of a typical MEGA-PRESS scan (10min).

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