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Abstract #1275

Optimisations for ultra-high resolution MRSI of the brain at 7 T: Towards even higher resolutions and faster measurements

Gilbert Hangel1,2, Bernhard Strasser3, Michal Povazan4,5, Eva Hečková1,2, Stephan Gruber1,2, Philipp Moser1,2, Lukas Hingerl1,2, Siegfried Trattnig1,2, and Wolfgang Bogner1,2

1High Feld MR Centre, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 4Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, 5F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Recently, ultra-high resolution (UHR-) MRSI of the brain at 7 T was successfully demonstrated, allowing metabolic mapping at near-anatomical resolution. With this work, we propose further optimised sequences, one for shorter measurement times of under 5 min and one for even higher in-plane resolutions down to 12 µL, which will allow a more flexible application of UHR_MRSI, and show their possibilities and limitations. Furthermore, the effects of slice thickness for UHR-MRSI were investigated with a second set of measurements.

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