Abstract #1256

Simultaneous PET and MRSI of Prostate Cancer

Kirsten Margrete Selnæs^1,2, Morteza Esmaeili¹, Nassim Tayari³, Tom Scheenen³, Mattijs Elschot¹, Arend Heerschap³, and Tone Frost Bathen¹

¹Department of Circulation and Medical Imaing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway, ²St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ³Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, Netherlands

Both positron emission tomography (PET) and magnetic resonance spectroscopic imaging (MRSI) can give important information about cancer metabolism. With an integrated PET/MR scanner, MRSI and PET images can be acquired simultaneously. The aim of this study was to examine possible correlations between ¹⁸F-Fluciclovine PET and MRSI measurements and evaluate their diagnostic performance in prostate cancer. The results showed a significant moderate correlation between both SUV_mean and SUV_max and the CCS/C ratio. A combination of the imaging outcomes derived from the integrated PET-MRSI modalities improved the localization accuracy of prostate cancer lesions.

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