Meeting Banner
Abstract #1227

Sub-millimetric 4D Flow MR in small intracerebral aneurysms at 7 Tesla with experimental verification in upscaled 3D printed replica.

Pierre-Francois Van de Moortele1, Mostafa Toloui1, Omid Amili2, Sean Moen3, Sebastian Schmitter1,4, Susanne Schnell5, Michael Markl5,6, Kamil Ugurbil1, Filippo Coletti2,7, and Bharathi Jagadeesan3,8,9

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Department of Aerospace Engineering and Mechanics, University of Minnesota, Minneapolis, MN, United States, 3Department of Neurosurgery, University of Minnesota, Minneapolis, MN, United States, 4Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 5Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 6Department Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, United States, 7St. Anthony Falls Laboratory, University of Minnesota, Minneapolis, MN, United States, 8Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 9Department of Neurology, University of Minnesota, Minneapolis, MN, United States

Asymptomatic intracerebral aneurysms of small size (<7mm) pose a difficult therapeutic challenge: left alone they may stay stable with no consequence or they may grow and/or rupture with devastating subarachnoid hemorrages. Pre-emptive treatment (surgical or endovascular) however carries non-negligible mortality and morbidity and there is no biomarker predicting these relative risk. Flow dynamics inside small aneurysms however could have a critical impact on their evolution. Here we investigate the use of 4D Flow MR to acquire submillimitric flow information in small aneurysms in vivo as well as in 3D printed up-scaled replica of actual aneurysms measured in patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here

Abstract Presentation Video